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Deflation starts on Round 31 and ends on Round 60, thus limiting hero leveling and featuring more challenging rounds than in Easy Standard. It disables income generation, so the full setup can be obtained at the start.
The defense must be able to cover all Bloon types, including their Camo variants. For example, Camo Purples appear on Rounds 45 and 48, and Camo Leads appear on Round 59.
The hero is important, despite them not leveling up as much, due to the limited cash. Utilize their abilities and use towers that they work the best with.
Attempt to not place down Tier 2 towers that are not Monkey Villages, as in general, a few strong Tier 3s and Tier 4s easily best many Tier 2s.
Monkey Commerce's discount is extremely helpful in getting the initial setup. Purchase it first, attempt to put down the entire final defense (including Villages) in its range for discount, upgrade the defense into cross-pathed Tier 3s, sell Monkey Commerce, and upgrade towers (if desired) into Tier 4s. Note that this is not recommended for Crossbow Master.