Healing Bloon excels in tempo decks, best deployed when there are large swarms of injured Bloons. The Bloon itself is a mild threat, but its On Play effect punishes opponents who rely on chip damage, especially after a board clear that didn't pop any Bloons. If the opponent tries to leak high-health Bloons, Healing Bloon can be used as a finisher.
Healing Bloon works best when combined with large amounts of Bloons with high and low HP, to force the opponent to avoid only focusing on single-target or groups, including Camo Bloons such as Camo Regrow Rainbows.
Healing Bloon's healing effect is immediate, unlike Prince of Darkness which favors continuous healing. Both are often seen in tempo, and give more overall health than most cards that only increase health.
Compared to a Ceramic Bloon, the Healing Bloon has 50 less HP and costs 1 Gold more.