Psi - Psi ignores line of sight blockers and can attack the Bloons anywhere on either path. He can also be placed close enough to the track to make use of Psionic Scream.
Heli Pilots — These towers can fly over obstacles and attack anywhere. Since Bloons only travel on one path at a time, this allows the Helis to maximize their damage potential against all Bloons.
Towers with a medium or smaller footprint can be placed between the paths and reliably beat the early game on their own.
Gallery
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Basic Deflation strategies
Basic Apopalypse strategies
Basic Half Cash strategies
Basic Alternate Bloons Rounds strategies
Basic Impoppable strategies
Basic CHIMPS strategies