Sharp Shooter works best when paired with damage buffs, effectively a 4x buff effect at best (assuming it's at max Ammo). Damage boosters such as Gwendolin and Super Monkey Fan Club work well with Sharp Shooter.
It is recommended to use the first shot on a high-HP Bloon, and then use the two ordinary shots as if Sharp Shooter has base Attack Power.
Anything that gives Temporary Ammo instead of ordinary ammo is much stronger with Sharp Shooter, making it work well with Heroes like Ezili.
This article or section needs more screenshots. See the screenshot guidelines for more information on what screenshots are needed and how to add them. The editor that added this notice elaborates: Sharp Shooter max ammo damage value (on Monkey), Sharp Shooter non-max ammo damage (on Monkey), and buffing a Sharp Shooter with damage buffs from Gwen and SMFCs
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Firstlook icon
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Multiple Sharp Shooters in the Firstlook Test
Sharp Shooters with and without Ammo, with double AP when full