Super Monkey Storm is expensive but the strongest of the Rare board clearing cards. Save it for a last resort against a swarm of high-HP bloons, such as an all-out rush.
It's an expensive board clear, making it difficult to afford against aggro, unless the opponent's only aggro push is delayed too much. However, it's capable of destroying a lot of Bloon types in one go. Having high damage at once, it is the only enemy-only board clear that can one-shot certain Armored Bloons such as Lead Bloons, Lead Coating Bloons, and Double Lead Bloons.
Two of them deal 300 damage, enough to wipe out almost all Camo rushes in a single turn, except DDTs. However, this combo requires max Gold.
Like with all board clears, Prince of Darkness and Healing Bloon increase the difficulty of wiping out large amounts of high-HP Bloons, such as in tempo decks that contain masses of Large Bloons. Likewise is the case with Regrows that have more than 150 Health, including Camo Regrow Rainbows and Camo Regrow Ceramics.