MOAB Strike is used similarly to Bloon Strike, although there are more cost-efficient ways to deal the same amount of damage or more to the enemy Hero. However, using Amelia the Amazing's Act of Power to lower the cost of this card to 3 Gold can make it more efficient in some situations.
Two Bloon Strikes cost 1 less Gold in total compared to a MOAB Strike. However, with a single Amelia's Act of Power, two Bloon Strikes cost the same Gold in total, due to missing 1 Gold of discounts.
A Pink Bloon usually does the job of finishing off a low-HP opponent, if not accounting for Defenders, enemy Quincy's passive, Adora's passive, or Hero Protection, for 3 less Gold, and additionally is capable of gaining health buffs.
Hastening Bloon costs 1 less Gold, and Quick Ready the same cost, and can potentially move a higher damaging Bloon to zero delay.
Players seeking to evade Adora tend to use Ability Ban, which costs 2 Gold, so the remaining Gold can be bought for other things.
Against this, have a Jungle's Bounty Druid to force the opponent to not play the card. You may also want to keep your health above 100 or else your opponent can play this card or a Pink Bloon and defeat you.